Dear colleagues,
We are delighted to invite you to an international workshop on *Developing
New Models for Pharmaceutical Innovation: towards a Mixed Economy*. This
will be held in Amsterdam on Monday 15 July and will bring together key
international organisations, policymakers, scholars, clinicians, patients,
SME pharma representatives, and other involved practitioners to discuss
alternative, collaborative ways of developing new medicines. See summary
below.
We are delighted to have a number of great speakers already confirmed,
including Els Torreele
, Michael Hopkins ,
Susi
Geiger , Ellen Moors
, Donald Lo
, Jon de Vlieger
, Saco de Visser
and Roz Scourse
from Médecins
Sans Frontières (MSF)
- and
there are more to come!
This workshop is supported by EATRIS
, Future Affordable
Sustainable Therapies , and
Lygature and sponsored by Social
Pharmaceutical Innovation (SPIN)
,
Utrecht
University , iHuman,
University of Sheffield
,
and University College Dublin
.
The event has already sparked a great deal of interest and we expect it to
be oversubscribed, so we encourage you to register soon. This can be done
via: https://forms.gle/i7EzuWBoNkY68zLa8.
For more information please contact Tineke (tineke.kleinhout-vliek@ucd.ie)
or Paul (paul.martin@sheffield.ac.uk). We look forward to seeing you in
Amsterdam!
Best wishes,
Tineke Kleinhout-Vliek, University College Dublin
Paul Martin, University of Sheffield
Wouter Boon, Utrecht University
*International Workshop “Developing New Models for Pharmaceutical
Innovation: towards a Mixed Economy”*
*Date: *Monday 15 July 2024, Schipluidenlaan 4, Amsterdam, and online
Several initiatives in the public and non-profit sectors seek new ways of
discovering, developing, and manufacturing a broad range of medicines and
medical products. These initiatives include repurposing (generic) drugs,
collaborative platforms, public-private partnerships, patient and
clinician-led development of medicines, and public-sector manufacturing.
They often target tropical diseases, (ultra) rare conditions, and other
areas of high need, such as anti-microbial resistance.
The idea of a "mixed economy of pharmaceutical innovation" highlights these
alternative models, multiple systems, and different economies complementary
to the 'mainstream' pharmaceutical industry. These initiatives do not
directly compete with industry in creating novel therapies but primarily
seek to ensure access to medicines for all.
Public policy should actively support the creation of alternative models,
sometimes labelled 'social pharmaceutical innovations' (SPINs), and thus
advance a mixed economy. Developing such policies requires a focused
discussion of critical issues, including:
*1) Funding *– developing new models of circular or sustainable funding for
non-profit or low-margin commercial innovation is critical to support a
vibrant third sector. How can we go beyond a reliance on philanthropy and
government research funding in the long run?
*2) Procurement *– many health care systems have rigid policies on drug
pricing that make it hard to differentially price repurposed drugs or
support public sector manufacturing. What new payment systems could be
introduced to support alternative innovation models?
*3) Regulation *– there are many regulatory barriers to non-commercial
actors holding marketing authorisation or supporting late-stage drug
development. These barriers include liability and data collection concerns.
What novel institutional mechanisms may address these issues?
*4) Collaboration *– new models of innovation require important changes in
the relationship between the public/non-profit and private sectors in the
division of responsibilities and benefit sharing. How can a new social
contract be negotiated that supports public health-driven innovation whilst
incentivising private investment in lower-cost drug development?
Paul Martin
Professor, Sociology of Science and Technology
Department of Sociological Studies
University of Sheffield
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